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In cell cultures, homocysteine induces programmed cell death in human vascular endothelial cells by interfering in protein syntheses.5 Because of its similarity to methionine, homocysteine can enter the protein biosynthetic apparatus

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A single-site study in a cohort of asthma and obesity (BMI 35–40 kg/m2) demonstrated the addition of exercise to dietary and behavioral counseling increased weight loss, improved asthma control scores, reduced inflammatory biomarkers and comorbid depression and sleep apnea 14, 15